Jaime Guevara-Aguirre Selected Research

Laron Syndrome (Syndrome, Laron)

1/2018	Treatment of growth failure in the absence of GH signaling: The Ecuadorian experience.
1/2017	Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans.
5/2014	The E180splice mutation in the GHR gene causing Laron syndrome: witness of a Sephardic Jewish exodus from the Iberian Peninsula to the New World?
6/2007	Effects of heterozygosity for the E180 splice mutation causing growth hormone receptor deficiency in Ecuador on IGF-I, IGFBP-3, and stature.

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Jaime Guevara-Aguirre Research Topics

Disease

11	Insulin Resistance 01/2021 - 02/2011
7	Neoplasms (Cancer) 01/2022 - 02/2011
6	Obesity 01/2020 - 03/2012
4	Laron Syndrome (Syndrome, Laron) 01/2018 - 06/2007
3	Type 2 Diabetes Mellitus (MODY) 01/2018 - 02/2004
2	Diabetes Mellitus 08/2020 - 01/2016
1	Carcinogenesis 01/2022
1	Chagas Disease (American Trypanosomiasis) 01/2022
1	Cognitive Dysfunction 01/2022
1	Glucose Intolerance 08/2020
1	Chronic Pain 06/2019
1	Substance-Related Disorders (Drug Abuse) 06/2019
1	Hyperinsulinism (Hyperinsulinemia) 01/2018
1	Overnutrition 01/2015
1	Inborn Genetic Diseases (Disease, Hereditary) 05/2014
1	Melanoma (Melanoma, Malignant) 03/2014
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 03/2012
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2012
1	Insulin-Like Growth Factor I Deficiency 03/2008
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 08/2007
1	Hypoglycemia (Reactive Hypoglycemia) 02/2006
1	Body Weight (Weight, Body) 02/2006
1	Growth Disorders 02/2002

Drug/Important Bio-Agent (IBA)

14	Insulin (Novolin)FDA Link 01/2021 - 02/2004
10	Insulin-Like Growth Factor I (IGF-1)IBA 01/2022 - 02/2006
6	Growth Hormone (Somatotropin)IBA 01/2022 - 03/2008
4	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 02/2004
3	Insulin-Like PeptidesIBA 01/2022 - 02/2006
3	Oral SpraysIBA 08/2007 - 02/2004
2	Somatotropin Receptors (Growth Hormone Receptor)IBA 01/2021 - 05/2014
2	LeptinIBA 07/2015 - 02/2002
1	Tramadol (K315)FDA LinkGeneric 06/2019
1	Aromatic Amino Acids (Aromatic Amino Acid)IBA 01/2019
1	Peptides (Polypeptides)IBA 01/2018
1	Indicators and Reagents (Reagents)IBA 07/2015
1	Branched-Chain Amino AcidsIBA 07/2015
1	AdipokinesIBA 07/2015
1	AdiponectinIBA 07/2015
1	Proteins (Proteins, Gene)FDA Link 03/2014
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 02/2011
1	Codon (Codons)IBA 03/2008
1	Insulin-Like Growth Factor Binding Protein 3IBA 06/2007
1	Hypoglycemic Agents (Hypoglycemics)IBA 02/2004
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 02/2004

Therapy/Procedure

1	Protein-Restricted Diet (Diet, Protein Restricted) 03/2014
1	Injections 11/2004
1	Therapeutics 02/2004